Jennifer White, of Bedford, was arrested as a result of a weeklong investigation conducted by the Putnamville facility's Internal Affairs staff.
White was intercepted Tuesday by PCF Correctional Lt. Candice Fielden as she attempted to enter the facility to visit her boyfriend, offender Robert Douglas.
White was immediately escorted to the Internal Affairs office, where she voluntarily surrendered SPICE.
Correctional Police Officer David Wire placed White under arrest and transported her to the Putnam County Jail, where she was charged with conspiracy to trafficking a controlled substance with an offender, a Class C felony.
Douglas, 27, of Indianapolis, is serving a sentence for theft with a projected release date of Aug. 23, 2012.
He has been placed in administrative segregation and could face criminal charges pending the outcome of the investigation.
SPICE, also known as K-2, is a synthetic drug that when consumed emulates the effects of cannabis.
"Every opportunity is taken to apprise visitors that trafficking in our facility will not be tolerated and that anyone attempting to do so or collaborating with another to participate in criminal behavior will be prosecuted to the fullest extent of the law," PCF Superintendent Stanley Knight said.
"I commend our staff for their diligent efforts and hope that this serves as a warning to any person or persons contemplating engaging in illegal activity in our prisons," Knight added.